Separation and identification of antidepressants by acrylate-based monolithic column capillary electrochromatography
1Department of Chemistry, Florida International University, Miami, FL, USA.
Abstract:
This paper details a method for separation and identification of six antidepressant compounds using an acrylate-based porous monolithic capillary. Detection takes place using CEC coupled with UV or mass spectrometric detection. The CEC-UV method provides an effective and efficient method for the separation and identification of the analytes. Spiked urine samples were utilized to check method capability, and a liquid-liquid extraction procedure was developed to perform sample extraction. Detection limits ranged from 10 to 30 ng/mL.
More Related Videos
Related Concept Videos
Ion-Exchange Chromatography
Capillary Electrophoresis: Applications
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Affinity Chromatography
Electrophoresis: Overview
There...
High-Performance Liquid Chromatography: Types of Detectors
Types Of Column Chromatography
Gel Filtration Chromatography
When the...


