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Under Pressure: When a Transformed Environment Pushes Cells to Malignancy.

María García-Fernández1, Simón Méndez-Ferrer1

  • 1Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Haematology, University of Cambridge, and National Health Service Blood and Transplant, Cambridge Biomedical Campus, CB2 0PT Cambridge, UK.

Cell Stem Cell
|November 5, 2016
PubMed
Summary

Mutated mesenchymal stem/progenitor cells (MSPCs) can drive cancer development. This study reveals how these altered cells transform healthy hematopoietic cells, promoting a malignant-prone state and contributing to oncogenesis.

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