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[Biological sorption in immunoneurologic diseases].

R I Novikova, V P Shano, T E Abashina

    Vrachebnoe Delo
    |June 1, 1989
    PubMed
    Summary

    Extracorporeal heterospleen (splenic sorption) reduced intensive care time by 1.5 times and mortality by 33% in patients with myasthenia and Guillain-Barré syndrome. This treatment removes autoimmune factors, aiding nervous system recovery.

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    Area of Science:

    • Neurology
    • Immunology
    • Intensive Care Medicine

    Background:

    • Myasthenia gravis and Guillain-Barré syndrome are severe autoimmune neurological disorders.
    • Current treatments often involve intensive care and may have limitations.

    Observation:

    • A study involved 17 patients (9 with myasthenia, 8 with Guillain-Barré syndrome).
    • All patients underwent a complex intensive therapy program including extracorporeal heterospleen (splenic sorption).
    • Forty-one splenic sorption perfusions were performed.

    Findings:

    • Splenic sorption reduced intensive care and reanimation treatment duration by 1.5 times.
    • Mortality was reduced by 33% in the treated patient group.
    • The procedure effectively removed humoral autoallergic factors.

    Implications:

    • Splenic sorption offers a promising therapeutic option for severe autoimmune neurological conditions.
    • This method can improve patient outcomes and reduce healthcare resource utilization.
    • Further research into biological sorption for neurological diseases is warranted.

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