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Advances in allergen immunotherapy in 2015
1Division of Allergy, Pulmonary, Critical Care, and Sleep Medicine, University of Wisconsin, Madison, Wis.
The Journal of Allergy and Clinical Immunology
|November 8, 2016
Summary
Advances in allergen immunotherapy (AIT) in 2015 focused on improving effectiveness and safety. Research explored optimal treatments, newer administration routes, and biomarkers for monitoring patient progress.
Area of Science:
- Allergy and Immunology
- Immunotherapy Research
Background:
- Allergen immunotherapy (AIT) has a long history of use, exceeding 100 years.
- Ongoing research aims to optimize treatment approaches and elucidate underlying mechanisms of AIT.
Purpose of the Study:
- To review significant advances in allergen immunotherapy (AIT) during 2015.
- To discuss improvements in the effectiveness, safety, and mechanisms of sublingual and oral immunotherapy.
Main Methods:
- Review of international expert guidelines on AIT.
- Analysis of recent developments in hypoallergenic vaccines, novel administration routes, and therapeutic regimens.
- Discussion of biomarkers for monitoring immunotherapy.
Main Results:
- Significant advancements in AIT were reported in 2015.
- Focus on enhancing safety through hypoallergenic vaccines and improving efficacy via new routes and regimens.
- Biomarkers are being explored for monitoring treatment effectiveness.
Conclusions:
- The year 2015 brought notable progress in allergen immunotherapy.
- Continued research is vital for refining AIT strategies, including safety, efficacy, and monitoring.
- Addressing unmet needs in AIT remains a key focus for the scientific community.
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