[Compliance in forms of drug therapy with special reference to aspects of trust]

This study investigates the compliance in respect to medication. Because of the so far wide ranging and often methodologically differing ways of documentation and description of compliance, we first had to start by determining the term in accordance with the current scientific discussion. The following step was to demonstrate similarities and differences of the compliance in relation to trust by empirical data. Empirical methods: A sample of ten persons was interviewed by a semi-standardized questionnaire, in order to find the constructs of compliance and trust in reference to the medication. These interviews were based on a theoretical analysis. The evaluation of the interview showed 21 constructs for compliance and 14 constructs for the description of trust in the therapeutic situation. These constructs were combined with control questions in a likert-rated questionnaire, which was answered by 160 representative test persons. From the thus required data 6 factors of compliance and 5 factors of the trust were isolated in a factor analysis. A comparison of compliance and trust by a regression-analysis showed that it is not possible to exchange both constructs completely. The limit of the exchangeability is given by medical factors such as side-effects or the knowledge about a given medication. Thus it was demonstrated that it is possible to increase compliance by trust. However, compliance is made up by different factors which are hardly modified by trust.