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Updated: Jul 9, 2026
10:41
Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
Diffuse type testicular seminoma in a stallion
G Farjanikish1, M Sayari2, A Raisi3
1Department of Pathobiology, Faculty of Veterinary Medicine, Lorestan University, Khorram Abad, Iran.
Comparative Clinical Pathology
|November 8, 2016
Summary
A diffuse seminoma, a type of testicular cancer, was diagnosed in a 7-year-old stallion. Immunohistochemistry confirmed the diagnosis, and no recurrence or metastasis was observed after nine months.
Area of Science:
- Veterinary Pathology
- Oncology
- Equine Medicine
Background:
- Testicular tumors are uncommon in stallions.
- Seminomas are the most common testicular germ cell tumor in horses.
Purpose of the Study:
- To report a case of diffuse seminoma in a stallion.
- To describe the gross, histological, and immunohistochemical features of the tumor.
- To evaluate the prognosis after treatment.
Main Methods:
- Gross examination of the excised testicle.
- Histopathological evaluation of tumor tissue.
- Immunohistochemical staining for C-KIT and OCT3/4.
Main Results:
- A 7-year-old stallion presented with a large, multinodular left testicular tumor (3.7 kg).
- Histopathology revealed diffuse sheets of neoplastic cells with eosinophilic cytoplasm and prominent nucleoli.
- Immunohistochemistry showed positive nuclear staining for C-KIT and negative staining for OCT3/4, consistent with seminoma.
Conclusions:
- The tumor was diagnosed as diffuse seminoma based on integrated diagnostic findings.
- The stallion showed no evidence of recurrence or metastasis nine months post-surgery, suggesting a favorable prognosis for this type of tumor.
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