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Pericardial Tamponade in an Adult Suffering from Acute Mumps Infection
Sascha Kahlfuss1, Robert Rainer Flieger1, Annette Mankertz2
1Department of Cardiology, HELIOS Clinical Medical Center Köthen, 06366 Köthen, Germany.
Abstract:
Here, we report a case of a 51-year-old man with acute pericardial tamponade requiring emergency pericardiocentesis after he suffered from sore throat, headache, malaise, and sweats for two weeks. Serological analyses revealed increased mumps IgM and IgG indicating an acute mumps infection whereas other bacterial and viral infections were excluded. In addition, MRI revealed atypical swelling of the left submandibular gland. Whereas mumps has become a rare entity in children due to comprehensive vaccination regimens in western civilizations, our case highlights mumps as an important differential diagnosis also in adults, where the virus can induce life-threatening complications such as pericardial tamponade.
Insights
Mumps infection in adults can lead to severe complications like pericardial tamponade, requiring emergency treatment. This case highlights the importance of considering mumps in adult differential diagnoses, even with widespread vaccination.
Area of Science:
- Infectious Diseases
- Cardiology
- Virology
Background:
- Mumps is a viral illness typically affecting children, with widespread vaccination significantly reducing its incidence in pediatric populations.
- While generally mild, mumps virus (Paramyxoviridae family) can cause serious complications, particularly in unvaccinated or under-vaccinated individuals.
- Adult presentation of mumps is less common, potentially leading to delayed diagnosis and management of associated severe sequelae.
Purpose of the Study:
- To report a rare case of acute pericardial tamponade secondary to mumps infection in an adult.
- To emphasize mumps as a critical differential diagnosis in adults presenting with symptoms suggestive of systemic viral illness and cardiac complications.
- To underscore the potential for life-threatening outcomes from mumps in the adult population.
Main Methods:
- Clinical case presentation of a 51-year-old male.
- Diagnostic workup included serological testing for mumps IgM and IgG antibodies.
- Magnetic Resonance Imaging (MRI) was utilized to assess for associated glandular swelling.
Main Results:
- The patient presented with symptoms of sore throat, headache, malaise, and sweats, progressing to acute pericardial tamponade.
- Serological tests confirmed acute mumps infection, with elevated mumps IgM and IgG levels.
- MRI revealed atypical swelling of the left submandibular gland, consistent with parotitis.
Conclusions:
- This case demonstrates that mumps can cause severe, life-threatening complications such as pericardial tamponade in adults.
- Healthcare providers should maintain a high index of suspicion for mumps in adults presenting with relevant symptoms and cardiac emergencies.
- The findings reinforce the need for continued vigilance regarding mumps, even in populations with high vaccination rates.
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