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Updated: Mar 12, 2026

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation
Published on: August 19, 2020
Cytomegalovirus-induced collapsing focal segmental glomerulosclerosis
Vanya Grover1, Meghana R Gaiki2, Maria V DeVita2
1Department of Medicine , North Shore-LIJ Health Care System-Lenox Hill Hospital , New York, NY , USA.
Abstract:
Collapsing glomerulopathy is an aggressive morphologic variant of focal segmental glomerulosclerosis which typically presents with nephrotic syndrome and rapidly progressive renal failure. Most cases of collapsing glomerulopathy are associated with human immunodeficiency virus infection. We present a rare case of collapsing glomerulopathy associated with acute cytomegalovirus (CMV) infection in an immunocompetent host with improvement in renal function after the treatment of CMV with ganciclovir. CMV may be an under-recognized cause of collapsing glomerulopathy which may respond to antiviral treatment.
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