Related Experiment Video
Updated: Mar 12, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Vocal fold mobility alteration reversed after thyroidectomy
Aline Paterno Miazaki1, Vergilius José Furtado Araújo-Filho1, Lenine Garcia Brandão1
1Head and Neck Surgery Discipline - Hospital das Clínicas - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil .
Benign thyroid enlargement can compress the recurrent laryngeal nerve (RLN), causing vocal cord immobility. Thyroidectomy often restores vocal fold function in these cases, highlighting the importance of surgical intervention.
Area of Science:
- Otolaryngology
- Endocrinology
- Neurology
Background:
- Vocal cord mobility derangement is often linked to recurrent laryngeal nerve (RLN) involvement, frequently due to thyroid malignancy.
- While uncommon, benign thyroid conditions can also cause vocal cord immobility through direct recurrent laryngeal nerve compression by enlarged goiters.
Observation:
- The study presents three cases of unilateral vocal cord palsy diagnosed via laryngoscopy.
- Patients presented with large, compressive goiters that were implicated in the vocal cord dysfunction.
Findings:
- Vocal fold mobility returned to normal in all three patients following thyroidectomy.
- This suggests that vocal cord immobility caused by benign compressive goiters is often reversible with surgical treatment.
Implications:
- These findings underscore the potential reversibility of vocal cord mobility disturbances after appropriate surgical intervention.
- Early surgical management is recommended to minimize nerve injury and preserve recurrent laryngeal nerve (RLN) integrity, potentially restoring function.
More Related Videos
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Larynx
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
The Hyoid Bone
Tracheostomy Decannulation
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...

