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Published on: July 16, 2018
A fluorescent probe for the selective detection of creatinine in aqueous buffer applicable to human blood serum
Siddhartha Pal1, Somenath Lohar1, Manjira Mukherjee1
1Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713104, West Bengal, India. pabitracc@yahoo.com.
Abstract:
A naphthalimide-based fluorescence light-up probe, FCP-Pd, has been designed and synthesized for selective detection and quantitation of creatinine in PBS buffer of pH 7.2 at 37 °C with a 'turn-on' response over a variety of interfering metal ions and/or anions and several biologically significant species. This probe is highly effective in estimating creatinine in human blood serum, which confirms the reliability and accuracy of this new system to be applied in clinical and toxicological analysis.
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