[Open injuries of the brain from the anatomo-clinical aspect]

A combined clinico-pathological and experimental investigation of the open traumatic brain lesions was performed. Clinical investigation of 266 patients is presented along with pathological findings in 9 autopsied brains of victims of craniocerebral trauma which died at different terms after the injury. Experimentally investigated were 25 cats with brain lesioned at various sites. The comparative characterization of the brain efferent systems' nervous fibers degeneration was presented and the topography of their distribution in the brainstem nuclear loci clarified. The data suggest that the state of brain conduction pathways is an important determinant of the pathogenesis of brainstem-related symptoms of acute brain hemisphere trauma.