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Related Concept Videos

Anatomical Positions01:11

Anatomical Positions

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In anatomy, several standard anatomical positions are used as references for describing the position and orientation of different body parts. These positions help provide a common frame of reference when discussing anatomical structures. The anatomical position is the standard reference point for describing the body's position and orientation. In this position:
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Mechanical Ventilation I: Indication and Settings01:29

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Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
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Mechanical Ventilation III: Noninvasive Ventilation01:23

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Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
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Mechanical Ventilation II: Invasive Ventilation01:23

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Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
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Ventilatory Modes01:14

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Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
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Related Experiment Video

Updated: Mar 12, 2026

An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient
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Infant position in neonates receiving mechanical ventilation.

May Rivas-Fernandez1, Marta Roqué I Figuls, Ana Diez-Izquierdo

  • 1Department of Pediatrics, Hospital Universitari General de Catalunya, Sant Cugat del Valles, Barcelona, Spain, 08190.

The Cochrane Database of Systematic Reviews
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Prone positioning may slightly improve oxygenation in newborns on mechanical ventilation (MV). However, evidence does not support sustained clinical benefits from specific body positions in neonates receiving MV.

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Area of Science:

  • Neonatal Intensive Care
  • Respiratory Physiology
  • Mechanical Ventilation

Background:

  • Non-supine positions, like prone, may improve respiratory parameters in ventilated patients.
  • Benefits of these positions are not well-defined for critically ill newborns on mechanical ventilation (MV).
  • This is an update of a review first published in 2005 and last updated in 2013.

Purpose of the Study:

  • To assess the effects of different positioning (supine vs. prone, lateral decubitus, quarter turn from prone) on short-term respiratory outcomes in newborns receiving MV.
  • To evaluate long-term effects on mortality, neuromotor, and developmental outcomes, and other complications of prematurity.

Main Methods:

  • Searched CENTRAL, MEDLINE, Embase, CINAHL for randomized and quasi-randomized trials.
  • Included 19 trials with 516 participants comparing various positions in newborns on MV.
  • Assessed risk of bias and used GRADE approach for evidence quality.

Main Results:

  • Prone positioning showed a small increase in arterial oxygen tension (PO2) and haemoglobin oxygen saturation (SpO2).
  • A slight improvement in desaturation episodes was noted, but long-term effects are unclear.
  • Limited data on adverse effects; one study suggested lower bacterial colonization in lateral positions.

Conclusions:

  • Evidence of low to moderate quality suggests prone positioning offers slight oxygenation improvement in neonates on MV.
  • No evidence supports specific body positions for sustained, clinically relevant improvements in neonates receiving MV.