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Updated: Mar 12, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
[Prognostic category of corneal transplantation in a referal center]
Karla Verdiguel-Sotelo1, Arturo Carrasco-Quiroz, Josué Rangel-Servín
1Clínica de Córnea y Superficie Ocular, Hospital General, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Ciudad de México, México. dalinde_karlaverdiguel@hotmail.com.
Background:
Penetrating keratoplasty is considered the most frequent and successfully performed organ transplantation. Indications of corneal transplantation have changed over time and they vary according to the country. Some risk factors for graft rejection, as age, corneal vascularization or ocular surgery, among others, have been identified. The aim was to identify the prognostic category, group and associated risk factors of patients registered in the database of corneal transplantation in the Centro Médico Nacional La Raza between 2011 and 2013.
Methods:
Cross-sectional, analytical, observational, retrospective and prospective chart study, with therapeutic and optical purposes, of patients from the aforementioned database of corneal transplantation.
Results:
We obtained 539 records. The most frequent diagnosis was keratoconus (29.1 %), followed by corneal scars (27.8 %), and pseudophakic bullous keratopathy (25.6 %). Of all patients, 57.5 % corresponded to the prognostic category 2, with a very good prognosis of corneal transparency.
Conclusion:
The most frequent diagnosis in the database of corneal transplant was keratoconus. It is necessary an update of the prognostic classification taking into account all known factors associated, in order to be more accuarte in the prognosis of corneal transplantation.
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