Related Experiment Video
Updated: Mar 12, 2026

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
Published on: February 26, 2019
Gastrointestinal hormones and the gut connectome
1aDepartment of Medicine bDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA.
Purpose Of Review:
Provision of adequate nutrients by the gut is essential for survival and essential behaviors are linked to the proper ingestion and digestion of food. Recently, a new neural connection has been reported between sensory cells of the gut epithelium and the nervous system that mediates signals from the gut to the brain.
Recent Findings:
This review describes how the gut senses its environment, relays those signals to the brain, and how the brain influences the gut.
Summary:
This gut-brain connection provides a pathway for how the body handles food.
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