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Follow-up study on children with infective endocarditis
J Schollin1, B Bjarke, G Wesström
1Department of Paediatrics, Orebro Medical Center Hospital, Stockholm, Sweden.
Acta Paediatrica Scandinavica
|July 1, 1989
Summary
This study followed 36 children with infective endocarditis, finding they generally recovered well. Long-term outcomes were positive, with few recurrent infections or late deaths in this pediatric cardiology research.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Longitudinal Studies
Background:
- Infective endocarditis (IE) is a serious infection affecting heart valves.
- Long-term outcomes in children after IE require further investigation.
Purpose of the Study:
- To assess the long-term health and cardiac function in children previously diagnosed with infective endocarditis.
- To evaluate the incidence of recurrent infections, late mortality, and sequelae in this cohort.
Main Methods:
- A follow-up study of 36 children with a history of infective endocarditis (1971-1980).
- Data collection included questionnaires and comprehensive non-invasive cardiac examinations with exercise testing.
- Study duration comprised 406 patient-years.
Main Results:
- Four late deaths and three recurrent endocarditis attacks occurred over 406 patient-years.
- Two patients required surgery for the initial infection; five developed intracardiac sequelae.
- An ability index indicated a positive overall outcome for the group.
Conclusions:
- Children who have had infective endocarditis can achieve good long-term outcomes.
- Prophylactic antibiotics and timely management of sequelae may contribute to favorable results.