Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sensation01:21

Sensation

1.8K
Sensory receptors are specialized neurons that respond to specific types of external stimuli, initiating the process known as sensation. This occurs when sensory input, such as light entering the eye, is detected by these receptors, causing chemical changes in the cells of the retina. These cells then convert the sensory stimulus into action potentials that are transmitted to the central nervous system, a process termed transduction.
Absolute thresholds can quantify the sensitivity of sensory...
1.8K
Exercise Stress Test01:26

Exercise Stress Test

1.7K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impairments in mitochondrial dynamics and morphology in skeletal muscle of breast cancer patients after a single paclitaxel administration.

Experimental physiology·2026
Same author

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia.

The Journal of physiology·2026
Same author

The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia.

The Journal of physiology·2026
Same author

Cost-effective mitigation strategies for air quality management in Uttar Pradesh, India.

Journal of environmental management·2026
Same author

NF-κB signaling drives rapid skeletal muscle atrophy in patients with breast cancer: the cost of fighting cancer with chemotherapy.

American journal of physiology. Cell physiology·2026
Same author

Feasibility and Potential Effects of Exercise Training Combining Eccentric and Concentric Cycling in Patients With Breast Cancer.

European journal of sport science·2026
Same journal

Which Strength Qualities Matter Most for Sprinting? Partitioning Unique and Shared Variance in a Multivariable Model.

European journal of sport science·2026
Same journal

Compensatory Effects of Joint Bracing From a Kinetic Chain Perspective: Lower Limb Movement Coordination Analysis During Badminton Lunge Movements.

European journal of sport science·2026
Same journal

Community-Based High-Intensity Multimodal Training: A Mixed-Method Evaluation of a Randomised Control Trial.

European journal of sport science·2026
Same journal

The Effect of Strength Training During Chemotherapy in Women With Breast Cancer on Serum Cytokine Concentrations and Skeletal Muscle Autophagy-Related Proteins.

European journal of sport science·2026
Same journal

Previous Hamstring Injury Does Not Impact Biceps Femoris Long Head Fascicle Length and Eccentric Knee Flexion Strength Changes Following a Low-Volume Resistance Training Intervention in Elite Under-20-Year-Old Male Gaelic Footballers.

European journal of sport science·2026
Same journal

Differences in Physical Fitness and Health-Related Variables Between Older Adults With Versus Without Self-Reported Impairments in Activities of Daily Living: A Population-Based Study.

European journal of sport science·2026
See all related articles

Related Experiment Video

Updated: Mar 12, 2026

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

1.7K

The 'sensory tolerance limit': A hypothetical construct determining exercise performance?

Thomas J Hureau1, Lee M Romer2, Markus Amann1

  • 1a Department of Medicine , University of Utah , Salt Lake City , UT , USA.

European Journal of Sport Science
|November 9, 2016
PubMed
Summary
This summary is machine-generated.

Neuromuscular fatigue limits exercise performance through central and peripheral factors. New concepts like the

Keywords:
Central commandexercise limitationfatiguemuscle afferent feedbackperformance

More Related Videos

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

21.5K
Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test
06:00

Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test

Published on: July 27, 2015

13.2K

Related Experiment Videos

Last Updated: Mar 12, 2026

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

1.7K
Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

21.5K
Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test
06:00

Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test

Published on: July 27, 2015

13.2K

Area of Science:

  • Exercise Physiology
  • Neuroscience
  • Human Performance

Background:

  • Neuromuscular fatigue impacts exercise performance, arising from central and peripheral mechanisms.
  • Neural pathways, including feedback and feedforward processes, mediate interactions between central and peripheral fatigue.

Purpose of the Study:

  • To review the influence of feedback and feedforward mechanisms on exercise limitation.
  • To discuss the 'critical threshold of peripheral fatigue' hypothesis and the broader 'sensory tolerance limit' concept.

Main Methods:

  • Review of existing literature on neural control of exercise and fatigue.
  • Analysis of feedback mechanisms involving group III/IV sensory neurons.
  • Examination of feedforward mechanisms like central corollary discharge.

Main Results:

  • Group III/IV sensory neurons provide feedback from limb muscles to the central nervous system.
  • Central corollary discharge acts as a feedforward signal influencing fatigue and performance.
  • The 'critical threshold of peripheral fatigue' is task-specific, while the 'sensory tolerance limit' offers a more generalizable explanation for exercise tolerance.

Conclusions:

  • Feedback and feedforward mechanisms are crucial in regulating exercise intensity and preventing excessive muscle strain.
  • The 'sensory tolerance limit' provides a comprehensive framework for understanding exercise limitation across different modalities.