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Updated: Mar 12, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
Anterior interosseous nerve and posterior interosseous nerve involvement in neuralgic amyotrophy
Mao Akane1, Katsuyuki Iwatsuki1, Masahiro Tatebe1
1Department of Hand Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi 466-8560, Japan.
Objectives:
The aim of this study was to gain a better understanding of anterior interosseous nerve and posterior interosseous nerve involvement in neuralgic amyotrophy.
Methods:
In a retrospective chart review, 51 cases (49 patients) with anterior and posterior interosseous nerve syndrome were investigated in terms of their symptoms, course of disease, and prognosis.
Results:
Patients first presented with pain in 52.9% of cases. The location of the pain was distal to the shoulder in most cases (85.1%). Sensory involvement was found in 27.5% of patients, and patients with pain before paresis had fewer sensory symptoms (p=0.006). Neurolysis significantly improved Hand20 scores, but conservative treatment did not (p=0.020 vs. 0.204).
Conclusions:
Patients with anterior interosseous nerve and posterior interosseous nerve affection in neuralgic amyotrophy had less pain. Neurolysis can be superior to conservative treatment in the patients with focal constrictions and no spontaneous recovery.
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