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Somatic Comorbidity in Chronic Constipation: More Data from the GECCO Study.

Paul Enck¹, Johannes Leinert², Menno Smid²

¹Department of Internal Medicine VI, University Hospital Tübingen, Tuebingen, Germany.

Gastroenterology Research and Practice

|November 9, 2016

Summary

Individuals with chronic constipation often have other health conditions, making them older and with lower health status than those with functional constipation alone.

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Area of Science:

Gastroenterology
Internal Medicine
Epidemiology

Background:

Comorbidity in chronic constipation is understudied, despite constipation being a symptom of various disorders.
Constipation can be linked to neurological, systemic, intestinal, and non-intestinal conditions.

Purpose of the Study:

To investigate the prevalence and characteristics of somatic comorbidity in a population sample with constipation.
To compare individuals with constipation and comorbid conditions to those with presumed functional constipation.

Main Methods:

A telephone survey identified 1037 individuals with constipation.
589 participants completed a postal questionnaire on sociodemographics, symptoms, comorbidities, and medication.
Comorbid and non-comorbid constipation groups were compared.

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Main Results:

Individuals with somatic comorbidity and/or regular medication were older (63.8 vs. 43.7 years) and had lower health/social status than those with functional constipation.
Physical quality-of-life was significantly lower in the comorbid group.
Mental health domains differed between functional constipation subtypes.

Conclusions:

Somatic comorbidity is more prevalent than functional constipation alone in an unselected constipated population.
Constipation with comorbid conditions is associated with older age and poorer health status.