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Updated: Mar 12, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Simultaneous large bi-atrial device-related thrombi
Jonas Dominik Häner1, Christian Seiler2
1Department of Cardiology, Inselspital, University of Bern Hospital, 3010, Bern, Switzerland. jonas.haener@insel.ch.
Insights
This study reports a rare case of simultaneous thrombus formation. Both a pacemaker lead and a left atrial appendage closure device were affected in a patient with urothelial carcinoma.
Area of Science:
- Cardiology
- Oncology
- Medical Imaging
Background:
- Pacemaker leads and left atrial appendage closure devices are common in cardiovascular care.
- Thrombus formation is a known complication associated with these devices.
- Urothelial carcinoma is a type of cancer affecting the urinary tract.
Observation:
- A patient diagnosed with urothelial carcinoma presented with concurrent thrombus formation.
- The thrombus was associated with the pacemaker lead.
- Another thrombus was identified related to the left atrial appendage closure device.
Findings:
- Transesophageal echocardiography revealed simultaneous thrombus formation.
- The findings highlight a potential association between urothelial carcinoma and device-related thrombosis.
- This case underscores the importance of vigilant monitoring in patients with both cardiac devices and malignancy.
Implications:
- Further research is warranted to explore the potential link between urothelial carcinoma and increased thrombotic risk in patients with cardiac devices.
- This case may inform clinical practice regarding anticoagulation strategies and surveillance protocols.
- Understanding such rare complications is crucial for improving patient outcomes in complex medical scenarios.
Abstract:
Simultaneous appearance of a pacemaker-lead associated thrombus and a left atrial appendage closure device related thrombus in a patient with urothelial carcinoma shown in a transesophageal echocardiography.

