Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.7K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.6K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.6K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

2.2K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.2K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychiatric and neurological predictors of early ADHD medication discontinuation across the lifespan: a multinational study.

BMJ mental health·2026
Same author

Age at menarche and adverse pregnancy and perinatal outcomes: triangulating evidence from multivariable and Mendelian randomization analyses.

International journal of epidemiology·2026
Same author

Using human genetic variation to estimate the effect of lipoprotein(a) lowering on pregnancy outcomes.

medRxiv : the preprint server for health sciences·2026
Same author

Using human genetics to understand the effect of modulating targets of antihypertensive drugs in pregnancy.

medRxiv : the preprint server for health sciences·2026
Same author

Clinical Characteristics of Users of Weight Loss Drugs: Population-Based Case-Control Study.

Diabetes, obesity & metabolism·2026
Same author

Myocarditis after COVID-19 mRNA vaccination in Norway: a nationwide validation study.

Open heart·2026

Related Experiment Video

Updated: Mar 12, 2026

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.6K

Pre-eclampsia and childhood asthma.

Maria C Magnus1,2,3, Siri E Håberg4, Per Magnus5

  • 1Domain for Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway Maria.Christine.Magnus@fhi.no.

The European Respiratory Journal
|November 9, 2016
PubMed
Summary
This summary is machine-generated.

Pre-eclampsia shows a weak link to childhood asthma, primarily explained by preterm birth and shared family factors. This large study found little evidence of a direct association between pre-eclampsia and asthma development.

More Related Videos

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

11.1K
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.4K

Related Experiment Videos

Last Updated: Mar 12, 2026

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

16.6K
Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

11.1K
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.4K

Area of Science:

  • Obstetrics and Gynecology
  • Pediatrics
  • Epidemiology

Background:

  • Conflicting evidence exists regarding the association between pre-eclampsia and childhood asthma.
  • Previous studies have not formally analyzed the mediating role of preterm birth in this relationship.

Purpose of the Study:

  • To investigate the association between pre-eclampsia and childhood asthma at age 7.
  • To conduct a mediation analysis of preterm birth and a sibling comparison to control for unobserved confounding.

Main Methods:

  • Utilized Norwegian national registries (1999-2006) and the Norwegian Mother and Child Cohort Study (MoBa).
  • Employed log-linear regression and mediation analysis.
  • Performed sibling comparison analysis to assess unobserved familial confounding.

Main Results:

  • A weak positive association between pre-eclampsia and asthma was observed in the registry study (RR 1.31), but not consistently in the MoBa cohort.
  • Mediation analysis indicated that preterm birth partially explained the association (indirect effect 1.12).
  • Sibling comparison revealed no significant association between pre-eclampsia and asthma (OR 1.07), suggesting shared confounders.

Conclusions:

  • Little evidence supports a direct association between pre-eclampsia and childhood asthma.
  • The observed association is largely attributable to preterm birth and familial confounders.
  • Further research should consider these mediating and confounding factors.