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Published on: April 23, 2021
Transient Ischemic Attack and Cognitive Impairment: A Review.
Christine A Ganzer1, Andrea Barnes, Constance Uphold
1Questions or comments about this article may be directed to Christine A. Ganzer, PhD PMHNP, at Anne.Ganzer@gmail.com. She is an Assistant Professor, Hunter-Bellevue School of Nursing, Hunter College, New York, NY. Andrea Barnes, PhD ARNP-BC, is Nurse Practitioner, Primary Care, VA New York Harbor Healthcare System, Brooklyn Campus, Brooklyn, NY. Constance Uphold, PhD ARNP-BC FAAN, is Associate Director for Implementation and Outcomes Research, Geriatric Research Education and Clinical Center and Extended Care and Research Services, North Florida/South Georgia Veterans Health System; and Associate Professor, Department of Aging & Geriatric Research, University of Florida, Gainesville, FL. Alan R. Jacobs, MD, is Clinician, Private Practice, New York, NY.
Transient ischemic attack (TIA) can cause lasting cognitive deficits, impacting executive function, memory, and attention. Understanding these long-term effects is crucial for patient care and health behavior adherence.
Area of Science:
- Neurology
- Neuroscience
- Cognitive Science
Background:
- Transient ischemic attack (TIA) is defined by temporary focal neurological deficits due to ischemia.
- Historically, TIA symptoms resolved within 24 hours, but emerging evidence suggests persistent cognitive deficits.
- Microvascular brain damage may contribute to long-term effects beyond acute symptom resolution.
Purpose of the Study:
- To provide an overview of clinical factors for investigating cognitive deficits in post-TIA populations.
- To review TIA definitions and discuss the role of neuropsychological evaluation and neuroimaging.
- To highlight the importance of advanced practice nurses in managing TIA patients.
Main Methods:
- Review of existing literature on TIA definitions and cognitive outcomes.
- Discussion of neuroimaging techniques and their correlation with TIA.
- Examination of neuropsychological tests for evaluating cognitive deficits.
Main Results:
- Cognitive deficits, particularly in executive function, can persist for at least 7 days post-TIA.
- Evidence suggests permanent microvascular tissue damage in the brain following TIA.
- Subtle cognitive changes may hinder positive health behavior adoption.
Conclusions:
- The definition and diagnosis of TIA require further standardization, including neuroimaging and neuropsychological testing.
- Persistent cognitive deficits after TIA necessitate clinical consideration.
- Advanced practice nurses play a key role in assessing and managing cognitive effects in TIA survivors.
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