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The early diagnosis of testicular natural killer/t-cell lymphoma
Pei Shu1, Wenwu Ling, Chenjing Zhu
1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy. No. 17, section 3, Renmin Road South, Chengdu, Sichuan 610041, China. drmaxuelei@gmail.com.
Abstract:
Testicular natural killer/T-cell lymphoma is a rare aggressive extranodal lymphoma associated with Epstein-Barr virus infection. Time to diagnose is crucial as the disease is rapidly progressive and fatal. Early suspicion is documented by imaging studies and testicular biopsies which are key factors for diagnosing testicular natural killer/T-cell lymphoma. However, no reports have described the results of imaging studies. In this paper, contrast-enhanced ultrasonography (CEUS), fluorine-18-fuorodexoyglucose-positron emission tomography/computed tomography (18F-FDG PET/CT) and tumor biopsies were all diagnostic of testicular natural killer/T-cell lymphoma. The CEUS showed a clear hyperenhancement which strongly indicted malignant tumor. In conclusion, in our study, CEUS as a first line easy test, may help physicians to make an early diagnosis of the very rare case of testicular T-lymphoma.
