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Updated: Mar 12, 2026
A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Evaluating Loading Deflection of Distraction Osteogenic Rib in a Rabbit Model
Weimin Shen1, Chenlu Tang1, Junyi Yang1
1Department of Plastic Surgery, Nanjing Children's Hospital, Affiliated with Nanjing Medical University, Nanjing, China; and Department of Cardiothoracic Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Background:
The treatment of patients with partially atrophic rib and rib defects requires an ideal arc of the rib that has adequate bone length and width. To design and assemble a distraction device with a strain gauge, we need to establish an animal model for testing it during rib distraction osteogenesis.
Methods:
Osteotomies were performed at the same position in the fifth rib in 8 rabbits. Customized distraction devices attached to strain gauges were used to distract the ribs. After a month of distraction and consolidation, loading deflection gauges were used, and specimens were examined histologically to record bone formation.
Results:
Distraction osteogenesis was carried out successfully in all rabbits when the device used to distract the rib up to 4 cm.
Conclusions:
The device can be used for strain testing during rib distraction osteogenesis performed in a rabbit model. There was no significant difference in the loading deflection gauges of the bone between osteogenic and contralateral ribs. This animal model of costal distraction osteogenesis is successful.
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