Related Experiment Video
Updated: Mar 12, 2026

Comprehensive Profiling of Dopamine Regulation in Substantia Nigra and Ventral Tegmental Area
Published on: August 10, 2012
Noncoding RNA Regulation of Dopamine Signaling in Diseases of the Central Nervous System
William T Carrick1, Brandi Burks1, Murray J Cairns2
1Department of Chemistry, Georgia Southern University Statesboro, GA, USA.
Abstract:
Dopaminergic neurotransmission mediates a majority of the vital central nervous system functions. Disruption of these synaptic events provokes a multitude of neurological pathologies, including Parkinson's, schizophrenia, depression, and addiction. Growing evidence supports a key role for noncoding RNA (ncRNA) regulation in the synapse. This review will discuss the role of both short and long ncRNAs in dopamine signaling, including bioinformatic examination of the pathways they target. Specifically, we focus on the contribution of ncRNAs to dopaminergic dysfunction in neurodegenerative as well as psychiatric disease.
More Related Videos
Related Concept Videos
Neural Regulation
Drugs Affecting Neurotransmitter Synthesis
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
lncRNA - Long Non-coding RNAs
lncRNA - Long Non-coding RNAs
Regulation of Expression at Multiple Steps

