[A woman with subcutaneous nodules after buttock augmentation]

Area of Science:

• Cosmetic surgery
• Oncology
• Dermatology

Background:

• Buttock augmentation using injectable soft-tissue fillers is a common cosmetic procedure.
• Delayed adverse effects, such as granulomatous inflammatory nodules, can occur.

Observation:

• A 35-year-old woman diagnosed with early-stage Hodgkin's lymphoma presented with multiple subcutaneous densities.
• These densities were located in both gluteal regions and identified on computed tomography (CT) scans.

Findings:

• The subcutaneous densities were determined to be granulomatous inflammatory nodules.
• These nodules resulted from frequent prior injections of human collagen for cosmetic buttock augmentation.

Implications:

• This case highlights a potential diagnostic challenge in patients with a history of cosmetic procedures.
• It underscores the importance of considering filler-induced inflammation in the differential diagnosis of gluteal masses, even in the context of malignancy.