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Updated: Mar 12, 2026
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Published on: June 10, 2025
Primary localized cutaneous amyloidosis with lichen and poikiloderma-like lesions and an excellent response to
Han Ma1, Xiangyang Su1, Guoxing Zhu1
1Third Affiliated Hospital, Sun Yat-sen University - Guangdong, China.
Abstract:
Primary localized cutaneous amyloidosis is a skin-limited amyloidosis that does not involve internal organs. It is clinically subclassified into 3 general categories and some rare variants. However, there is considerable overlap within the classification. Though there are a variety of therapeutic measures, the treatment is often unsatisfactory, particularly when the disease is severe and extensive. We describe a rare case of primary localized cutaneous amyloidosis with lichen and poikiloderma-like lesions that showed an excellent response to systemic acitretin.
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