Henoch-Schönlein purpura with c-ANCA antibody in an adult
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Updated: Mar 12, 2026

Simultaneous Distinction of Monospecific and Mixed DFS70 Patterns During ANA Screening with a Novel HEp-2 ELITE/DFS70 Knockout Substrate
Published on: January 17, 2018
Pedro de Freitas Silva Torraca1, Bruna Corrêa de Castro1, Günter Hans1
1Universidade Federal de Mato Grosso do Sul (UFMS) - Campo Grande (MS), Brazil.
Abstract:
The Henoch-Schönlein purpura is the vasculitis associated with deposits of immunoglobulin A in small vessels. Its association with cytoplasmic antineutrophil cytoplasmic antibodies is possible, but rare. This vasculitis is uncommon in adults and the main clinic manifestations are purpuric lesions in lower limbs with gastrointestinal symptoms and renal involvement. The present work describes a rare case of Henoch-Schönlein purpura in an adult with cytoplasmic antineutrophil cytoplasmic antibodies.
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