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Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
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Nail clipping in onychomycosis.

Laura Bertanha1, Nilton Di Chiacchio1

  • 1Hospital do Servidor Público Municipal de São Paulo (HSPM-SP) - São Paulo (SP), Brazil.

Anais Brasileiros De Dermatologia
|November 10, 2016
PubMed
Summary

Accurate early diagnosis of onychomycosis is crucial. Nail clipping histopathology offers a sensitive, painless, and cost-effective method for diagnosing fungal nail infections, complementing traditional methods.

Area of Science:

  • Dermatology
  • Mycology
  • Pathology

Background:

  • Onychomycosis is the most common nail disease.
  • Accurate diagnosis is essential for effective treatment.
  • Current gold standard diagnostic methods (direct microscopy and culture) have variable sensitivity.

Purpose of the Study:

  • To evaluate the utility of nail clipping histopathology as an adjunctive diagnostic tool for onychomycosis.
  • To assess the sensitivity, ease of performance, cost-effectiveness, and patient experience associated with this method.

Main Methods:

  • Histopathological examination of distal nail plate clippings.
  • Comparison with direct mycological tests and culture.

Main Results:

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  • Nail clipping histopathology demonstrated high sensitivity for diagnosing onychomycosis.
  • The procedure is easy to perform, inexpensive, and rapid.
  • It is minimally dependent on examiner skill and is painless for patients.

    • Conclusions:

    • Nail clipping histopathology is a valuable and effective adjuvant diagnostic method for onychomycosis.
    • It offers a practical, sensitive, and patient-friendly alternative/complement to existing diagnostic techniques.