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Intrauterine insemination with washed sperm
J Szöllösi1, I Szilágyi, J Daru
1Department of Obstetrics and Gynecology, University Medical School, Szeged, Hungary.
Archives of Andrology
|January 1, 1989
Summary
Intrauterine insemination using washed sperm is effective for infertility caused by poor cervical mucus. Success depends on sperm quality, with severe deviations in the spermiogram predicting treatment failure.
Area of Science:
- Reproductive Medicine
- Infertility Treatment
- Sperm Preparation Techniques
Background:
- Intrauterine insemination (IUI) is a common infertility treatment.
- Sperm washing is crucial for removing contaminants and improving sperm quality for IUI.
- Cervical mucus hostility and poor sperm quality are significant causes of infertility.
Purpose of the Study:
- To evaluate the effectiveness of intrauterine insemination with washed semen.
- To identify factors influencing IUI success rates.
- To assess the impact of sperm quality and cervical mucus on IUI outcomes.
Main Methods:
- Couples underwent thorough examination based on WHO principles.
- Ovulatory cycles were monitored, tracking oestradiol, follicle size, and progesterone levels.
- Semen was washed to remove albumin components and bacteria before insemination.
- Insemination was performed in two distinct groups.
Main Results:
- Optimal oestradiol and follicle size observed on days 13-14, with progesterone increase on days 14-15.
- Good outcomes were achieved when infertility was due to poor cervical mucus.
- Treatment success was linked to spermiogram quality; severe deviations led to no success.
Conclusions:
- Intrauterine insemination with washed semen is a viable treatment for specific infertility cases.
- Sperm quality, particularly the absence of severe spermiogram deviations, is critical for IUI success.
- IUI is particularly beneficial for couples with cervical mucus hostility as the primary infertility factor.