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PRESENTATION AND MANAGEMENT OF PERFORATED PEPTIC ULCER DISEASE IN A TERTIARY CENTRE IN SOUTH SOUTH NIGERIA
A Dodiyi-Manuel1, P N Wichendu1, V C Enebeli1
1Department of Surgery, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.
Journal of the West African College of Surgeons
|November 11, 2016
Summary
Perforated peptic ulcer disease predominantly affects young males. Graham's omental patch repair is an effective treatment, with Helicobacter pylori eradication recommended post-surgery for better outcomes.
Area of Science:
- Gastroenterology
- Surgical Gastroenterology
- Epidemiology
Background:
- Perforated peptic ulcer disease (PUD) is a life-threatening complication requiring prompt medical and surgical intervention.
- Common causes include peptic ulcer disease, NSAID abuse, and gastric cancer.
Purpose of the Study:
- To investigate the epidemiological pattern and treatment outcomes of perforated peptic ulcer disease.
- To evaluate management strategies at the University of Port Harcourt Teaching Hospital (UPTH).
Main Methods:
- A retrospective study of 36 patients with perforated PUD managed at UPTH from January 2006 to December 2014.
- Data collected from case notes and analyzed using SPSS version 17.
Main Results:
- The study included 28 males and 8 females (3.5:1 ratio), with a mean age of 42.1 years.
- Duodenal perforations (72.2%) were more common than gastric perforations (27.8%).
- Graham's omental patch repair was performed in 88.9% of patients; 19.4% experienced surgical site infections, and the mortality rate was 11.1%.
Conclusions:
- Perforated peptic ulcer disease primarily affects young males.
- Graham's omental patch repair is an effective surgical approach.
- Helicobacter pylori eradication is a recommended adjunct to treatment.
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