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Related Experiment Video

Updated: Mar 12, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

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3D Myocardial Elastography In Vivo.

Clement Papadacci, Ethan A Bunting, Elaine Y Wan

    IEEE Transactions on Medical Imaging
    |November 11, 2016
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces 3D myocardial elastography using diverging waves for high-volume rate cardiac strain evaluation. It accurately maps lesions and cardiac function in 3D, improving diagnostic capabilities.

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    Related Experiment Videos

    Last Updated: Mar 12, 2026

    In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
    08:13

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    Published on: February 16, 2016

    20.3K
    3D Whole-heart Myocardial Tissue Analysis
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    High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
    11:50

    High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

    Published on: July 9, 2010

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    Area of Science:

    • Cardiovascular Imaging
    • Biomedical Engineering
    • Medical Physics

    Background:

    • Cardiac strain evaluation is crucial for assessing heart function.
    • Myocardial elastography uses radio-frequency (RF) data for local strain analysis.
    • Accurate 3D strain measurement is needed for cardiac inhomogeneities like ablation lesions.

    Purpose of the Study:

    • To develop and validate 3D myocardial elastography at high volume rates.
    • To assess local axial strain distribution in 3D.
    • To visualize and map cardiac tissue changes post-ablation.

    Main Methods:

    • Utilized 3D myocardial elastography with diverging wave transmits.
    • Employed a 2.5 MHz 2D matrix array for high volume rate acquisitions (2000 volumes/s).
    • Evaluated strain in canine subjects before and after radio-frequency ablation.

    Main Results:

    • Achieved high-volume rate 3D strain imaging, capturing cardiac cycle dynamics.
    • Demonstrated visualization of rapid events during the QRS complex.
    • Successfully mapped ablated regions with high contrast between normal and damaged myocardium.

    Conclusions:

    • 3D myocardial elastography with diverging waves enables accurate, high-volume rate cardiac strain assessment.
    • The technique effectively visualizes and quantifies tissue changes, such as RF ablation lesions.
    • This method holds potential for enhanced 3D regional strain distribution analysis in clinical cardiology.