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Updated: Mar 12, 2026

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Extraosseous 99mTc-methylene diphosphonate uptake on bone scan: Unusual scenario
Shashwat Verma1, Narvesh Kumar2, Subhash Chand Kheruka2
1Department of Nuclear Medicine, RMLIMS, Lucknow, Uttar Pradesh, India; Department of Nuclear Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India.
Abstract:
In nuclear medicine, 99mTc-methylene diphosphonate. (MDP) bone scan is one of the most commonly performed procedures. MDP uptake in nonosseous tissues is occasionally found in bone scan, and the knowledge of these kinds of extraosseous uptakes is of much clinical relevance. We report here two cases where bone scan showed extraosseous MDP uptake either hepatic or splenic apart from the physiological skeletal uptake.
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