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Published on: January 29, 2014
Auditory brain stem response and cortical evoked potentials in children with type 1 diabetes mellitus
Heba Mohammed Radwan1, Amani Mohamed El-Gharib1, Adel Ali Erfan2
1a Audiology Unit, Faculty of Medicine , Tanta University , Egypt.
Insights
Children with type 1 diabetes mellitus (T1DM) show delayed auditory brain stem responses (ABR) and cortical evoked potentials (CAEPs), indicating neural conduction abnormalities. Longer diabetes duration negatively impacts auditory function more than glycemic control.
Area of Science:
- Neuroscience
- Endocrinology
- Audiology
Background:
- Diabetes mellitus (DM) is a prevalent endocrine and metabolic disorder.
- Evoked potentials are crucial for assessing central nervous system neural pathway function.
Purpose of the Study:
- To evaluate the impact of type 1 diabetes mellitus (T1DM) on auditory brain stem response (ABR) and cortical evoked potentials (CAEPs) in children.
Main Methods:
- A control group of 20 healthy children and a study group of 30 children with T1DM were included.
- Standard audiological assessments, ABR, and CAEPs were performed on all participants.
Main Results:
- Children with T1DM exhibited delayed absolute latencies in ABR and CAEPs waves compared to controls.
- No significant differences in wave amplitudes were observed between the groups.
- A positive correlation was found between ABR wave latencies and the duration of DM, but not with glycated hemoglobin levels.
Conclusions:
- Delayed ABR and CAEPs latencies in children with T1DM suggest impaired neural conduction.
- The duration of diabetes mellitus significantly affects auditory function more than its glycemic control.
Conclusions:
Delay in ABR and CAEPs wave latencies in children with type 1DM indicates that there is abnormality in the neural conduction in DM patients. The duration of DM has greater effect on auditory function than the control of DM.
Background:
Diabetes mellitus (DM) is a common endocrine and metabolic disorder. Evoked potentials offer the possibility to perform a functional evaluation of neural pathways in the central nervous system.
Objectives:
To investigate the effect of type 1 diabetes mellitus (T1DM) on auditory brain stem response (ABR) and cortical evoked potentials (CAEPs).
Method:
This study included two groups: a control group (GI), which consisted of 20 healthy children with normal peripheral hearing, and a study group (GII), which consisted of 30 children with type I DM. Basic audiological evaluation, ABR, and CAEPs were done in both groups.
Results:
Delayed absolute latencies of ABR and CAEPs waves were found. Amplitudes showed no significant difference between both groups. Positive correlation was found between ABR wave latencies and duration of DM. No correlation was found between ABR, CAEPs, and glycated hemoglobin.
