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Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes

Yapan Yang1, Jingchao Li1, Wenke Xu2

  • 11 Department of Cardiology, Zhengzhou University People's Hospital, Zhengzhou, China.

The Journal of International Medical Research
|November 12, 2016
PubMed

Insights

Red thrombi in acute myocardial infarction patients indicate longer ischemic times and increased in-hospital major adverse cardiovascular events compared to white thrombi. This finding highlights the clinical significance of thrombus composition in ST-elevation myocardial infarction.

Area of Science:

  • Cardiology
  • Pathology

Background:

  • Acute myocardial infarction (AMI) is a critical cardiovascular event.
  • Thrombus composition in AMI can influence clinical outcomes.

Purpose of the Study:

  • To compare clinical and angiographic outcomes between red and white thrombi in ST-segment elevation myocardial infarction (STEMI) patients.
  • To identify predictors of thrombus composition in STEMI.

Main Methods:

  • Prospective study of 137 STEMI patients undergoing primary percutaneous coronary interventions.
  • Thrombus material classified as red or white based on pathology.
  • Analysis of clinical and angiographic data.

Main Results:

  • Red thrombi were observed in nearly two-thirds of cases.
  • The red thrombus group had significantly longer ischemic times.
  • Higher incidence of in-hospital major adverse cardiovascular events (MACE) in the red thrombus group (15.6% vs. 0%).
  • Ischemic time was the sole predictor of thrombus composition.

Conclusions:

  • Red thrombi in STEMI are associated with prolonged ischemia and worse in-hospital outcomes.
  • Thrombus pathology is a significant factor in STEMI management and prognosis.

Keywords:
Acute myocardial infarctionintracoronary thrombusischaemic timepathology

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