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Nanoparticle-based photoacoustic analysis for highly sensitive lateral flow assays
Yunfei Zhao1, Yin Huang1, Xiangwei Zhao2
1Department of Electrical and Computer Engineering, Iowa State University, Ames, Iowa 50011, USA. menglu@iastate.edu.
Nanoscale
|November 12, 2016
Abstract:
This paper demonstrates a photoacoustics-based lateral flow test that takes advantage of the strong interaction of light and gold nanoparticles to quantitatively detect a disease biomarker. For a commercially available lateral flow test strip, the photoacoustic analysis improved the detection limit by two orders of magnitude compared to colorimetric measurements.
