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Updated: Mar 12, 2026
Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
Published on: September 5, 2011
Developing a new algorithm for first and second trimester preeclampsia screening in twin pregnancies
Ron Maymon1,2, Alla Trahtenherts3, Ran Svirsky1,2
1a Institute of Ultrasound, Department of Obstetrics and Gynecology , Assaf Harofeh Medical Centre, Affiliated with the Sackler School of Medicine , Tel-Aviv , Israel.
Objectives:
Construct a new preeclampsia predicting algorithm in twins.
Methods:
Twins sampled at 10-13 and 16-20 gestational weeks and their marker values were log transformed into multiples of the gestation-specific medians (MoMs) for singletons and entered into a new logistic regression model with/without prior risk factors.
Results:
The cohort included 9 PE (18 samples) and 96 unaffected cases (175 samples) twin pregnant women. The algorithm constructed of PlGF, PAPP-A, PP13, Doppler UTPI, and MAP with prior risk factors generated an area under the curve of 0.918, 75% detection rate for 10% false-positive rate.
Conclusions:
The algorithm effectively forecasted twin risk to develop PE.
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