Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the role of post-partum ultrasound of cesarean delivery scar on subsequent pregnancy outcomes: a preliminary study.

BMC pregnancy and childbirth·2026
Same author

Sonography-Assisted Management of Suspected Retained Products of Conception upon Completion of the Puerperium: A Prospective Single-Center Study.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2026
Same author

Fetal urinary ascites caused by bladder rupture due to paraurethral cyst: a rare case.

Archives of gynecology and obstetrics·2026
Same author

Plasma RNA-Based Dual Screening for Early/Extreme Spontaneous Preterm Birth and Early Onset Preeclampsia to Enable Prevention.

Diagnostics (Basel, Switzerland)·2026
Same author

Fertility and Obstetric and Clinical Outcomes following Embolization Management of Symptomatic Pregnancy-Related Arteriovenous Malformations: Two Decades of Follow-up from a Tertiary Medical Center.

Ultraschall in der Medizin (Stuttgart, Germany : 1980)·2026
Same author

[Eppur Si Muove ("And Yet It Moves") - Women's Medicine in the 21st Century].

Harefuah·2026

Related Experiment Video

Updated: Mar 12, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

15.5K

Developing a new algorithm for first and second trimester preeclampsia screening in twin pregnancies.

Ron Maymon1,2, Alla Trahtenherts3, Ran Svirsky1,2

  • 1a Institute of Ultrasound, Department of Obstetrics and Gynecology , Assaf Harofeh Medical Centre, Affiliated with the Sackler School of Medicine , Tel-Aviv , Israel.

Hypertension in Pregnancy
|November 12, 2016
PubMed
Summary

A new algorithm effectively predicts preeclampsia (PE) risk in twin pregnancies using specific biomarkers and risk factors. This tool aids in early detection for improved maternal and fetal outcomes.

Keywords:
Doppler UTPIMAPPAPP-APP13PlGF

More Related Videos

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

27.8K
Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

20.5K

Related Experiment Videos

Last Updated: Mar 12, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

15.5K
Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

27.8K
Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

20.5K

Area of Science:

  • Maternal-Fetal Medicine
  • Biomarker Discovery
  • Predictive Analytics

Background:

  • Preeclampsia (PE) in twin pregnancies poses significant risks.
  • Accurate prediction of PE in twins is crucial for timely intervention.
  • Existing prediction models may not be optimized for twin gestations.

Purpose of the Study:

  • To develop and validate a novel algorithm for predicting preeclampsia in twin pregnancies.
  • To identify key biomarkers and risk factors for PE in the twin setting.
  • To improve the accuracy of PE risk assessment in multifetal gestations.

Main Methods:

  • Collected data from twin pregnancies at 10-13 and 16-20 weeks gestation.
  • Transformed marker values to multiples of the gestation-specific medians (MoMs) for singletons.
  • Utilized a logistic regression model incorporating placental growth factor (PlGF), pregnancy-associated plasma protein-A (PAPP-A), placental protein 13 (PP13), Doppler ultrasound pulsatility index (UTPI), mean arterial pressure (MAP), and prior risk factors.

Main Results:

  • The study included 9 preeclampsia cases (18 samples) and 96 unaffected cases (175 samples).
  • The developed algorithm, incorporating PlGF, PAPP-A, PP13, Doppler UTPI, MAP, and prior risk factors, achieved an area under the curve (AUC) of 0.918.
  • The algorithm demonstrated a 75% detection rate at a 10% false-positive rate.

Conclusions:

  • The novel algorithm effectively predicts preeclampsia risk in twin pregnancies.
  • The combination of specific biomarkers and clinical risk factors enhances predictive accuracy.
  • This tool offers a promising approach for early PE risk stratification in twin gestations.