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Multiple hereditary osteochondromata.

H A Peterson1

  • 1Section of Pediatric Orthopedics, Mayo Clinic, Rochester, Minnesota 55905.

Clinical Orthopaedics and Related Research
|February 1, 1989
PubMed
Summary
This summary is machine-generated.

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Multiple hereditary osteochondromata causes bone growths and can lead to deformities. Surgical interventions can effectively correct these deformities and alleviate associated symptoms.

Area of Science:

  • Orthopedics
  • Genetics
  • Skeletal Dysplasias

Background:

  • Multiple hereditary osteochondromata (MHO) is an autosomal dominant skeletal disorder characterized by multiple bone exostoses capped with cartilage.
  • Lesions predominantly affect long bone metaphyses but can occur elsewhere, including flat bones and vertebrae.
  • While sarcomatous transformation is rare (<1%), MHO frequently necessitates surgical intervention for pain, growth disturbances, and functional impairments.

Purpose of the Study:

  • To review the clinical manifestations of MHO.
  • To discuss surgical indications and outcomes for MHO.
  • To highlight effective surgical treatments for associated limb and joint deformities.

Main Methods:

  • Literature review of MHO, focusing on clinical presentation, surgical indications, and treatment outcomes.

Related Experiment Videos

  • Analysis of surgical techniques for managing MHO-related deformities, including limb lengthening and physeal stapling.
  • Review of corrective procedures for wrist, ankle, and knee deformities.

    • Main Results:

    • Surgical excision of osteochondromas effectively relieves pain, improves joint motion and cosmesis, and prevents progressive growth disturbances.
    • Wrist and ankle deformities, including ulnar/fibular shortening and diaphyseal bowing, are addressed by ulnar/fibular lengthening and hemiphyseal stapling.
    • Progressive genu valgum can be effectively corrected using physeal stapling of the distal femur or proximal tibia.

    Conclusions:

    • Surgical management of MHO is crucial for improving patient function and quality of life.
    • Specific surgical techniques offer effective correction for diverse MHO-associated skeletal deformities.
    • Timely surgical intervention can mitigate long-term complications and improve skeletal alignment in MHO patients.