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Updated: Mar 12, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
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An improved method for total organic iodine in drinking water
Rassil Sayess1, David A Reckhow1
1Department of Environmental and Water Resources Engineering, University of Massachusetts, Amherst, 01003, United States.
A new method accurately measures total organic iodine (TOI) in water. This rapid technique uses adsorption, combustion, and ICP-MS detection for reliable quantification of iodinated organic compounds.
Area of Science:
- Environmental Chemistry
- Analytical Chemistry
Background:
- Organically-bound iodine in water is a significant environmental parameter.
- Existing methods for measuring total organic iodine (TOI) can be complex and time-consuming.
Purpose of the Study:
- To develop a concise, rapid, and sensitive method for quantifying total organic iodine (TOI) in water samples.
- To optimize the method for maximum iodine recovery and minimal inorganic iodine interference.
Main Methods:
- Combines adsorption onto granular activated carbon (GAC), combustion, and trapping of combustion products.
- Utilizes offline inductively coupled plasma/mass spectrometry (ICP-MS) for iodide detection.
- Employs a full factorial experimental design to optimize analytical variables like sample pH, base addition, and ICP-MS wash solution composition.
Main Results:
- Optimized method achieves high recovery of iodine from model organic compounds.
- The developed treatment effectively rejects inorganic iodine.
- The method demonstrated effectiveness with both model compounds and field water samples.
Conclusions:
- The refined method provides a reliable and efficient approach for measuring organically-bound iodine in water.
- This technique offers a valuable tool for environmental monitoring and water quality assessment.
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