Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

640
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
640
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

488
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
488
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

652
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
652
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

441
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
441
Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

1.1K
The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
1.1K
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

293
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
293

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fifteen-minute consultation: Empowering children, young people and families through shared decision-making: a practical guide.

Archives of disease in childhood. Education and practice edition·2024
Same author

Selective Elimination and Rationalization of Cell-based Assays in Deceased Donor Kidney Transplant Crossmatching.

Transplantation direct·2024
Same author

National study on the risks of COVID-19 infection for paediatric kidney transplant recipients: a retrospective, cross-sectional study.

Archives of disease in childhood·2024
Same author

Increasing SARS-CoV-2 seroprevalence among UK pediatric patients on dialysis and kidney transplantation between January 2020 and August 2021.

Pediatric nephrology (Berlin, Germany)·2023
Same author

Long term outcomes following kidney transplantation in children who weighed less than 15 kg - report from the UK Transplant Registry.

Pediatric nephrology (Berlin, Germany)·2023
Same author

Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency.

The ocular surface·2022

Related Experiment Video

Updated: Mar 12, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

5.3K

Sensitization assessment before kidney transplantation.

Ben C Reynolds1, Kathryn J Tinckam2

  • 1Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Transplantation Reviews (Orlando, Fla.)
|November 13, 2016
PubMed
Summary

Pre-transplant assessment is crucial for kidney transplant success. Advanced HLA typing and flow cytometry improve immunological risk evaluation for better patient outcomes.

More Related Videos

Measurement of T Cell Alloreactivity Using Imaging Flow Cytometry
09:04

Measurement of T Cell Alloreactivity Using Imaging Flow Cytometry

Published on: April 19, 2017

14.0K
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

16.7K

Related Experiment Videos

Last Updated: Mar 12, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

5.3K
Measurement of T Cell Alloreactivity Using Imaging Flow Cytometry
09:04

Measurement of T Cell Alloreactivity Using Imaging Flow Cytometry

Published on: April 19, 2017

14.0K
Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

16.7K

Area of Science:

  • Nephrology and Immunology
  • Transplantation Science

Background:

  • Kidney transplantation is the optimal treatment for end-stage renal disease, enhancing survival and quality of life.
  • Pre-transplant immunological assessment is vital for estimating donor-recipient risk and guiding interventions.
  • Understanding a patient's immunological history is fundamental for successful kidney transplant outcomes.

Purpose of the Study:

  • To review the pre-transplant histocompatibility assessment process for kidney transplant recipients.
  • To discuss the evolution and current methodologies in immunological risk assessment.
  • To highlight the importance of collaboration between HLA laboratories and transplant clinicians.

Main Methods:

  • Review of current methodologies for pre-transplant immunological assessment.
  • Discussion of flow cytometric analyses and molecular HLA typing techniques.
  • Examination of the interpretation of histocompatibility data.

Main Results:

  • Rapid evolution of methodologies, including flow cytometry and advanced HLA typing.
  • Increased availability of comprehensive molecular methods for donor and recipient HLA typing.
  • Growing recognition of the essential communication between HLA labs and transplant clinicians.

Conclusions:

  • Comprehensive pre-transplant assessment is key to optimizing kidney transplant access and success.
  • Current technologies offer improved methods for estimating immunological risk.
  • Effective interpretation and clinical dialogue are crucial for maximizing transplant outcomes.