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Updated: Mar 12, 2026

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
T2*-based MR imaging of hyperglycemia-induced hemichorea-hemiballism
Fang Yu1, Andrew Steven2, Lee Birnbaum3
1Department of Radiology, Massachusetts General Hospital, 55, Fruit Street, Boston, MA 02114, USA.
Introduction:
Hyperglycemia can induce hemichorea-hemiballism, especially in elderly type II diabetics. CT and MRI findings include hyperdensity and T1-shortening in the contralateral lentiform nucleus, respectively. This study explores the associated imaging findings on T2*-based sequences.
Methods:
Six patients with clinically documented hyperglycemia-induced hemichorea-hemiballism who had undergone MR imaging with a T2*-based sequence (T2* gradient echo or susceptibility-weighted imaging) were included in this retrospective case series.
Results:
All six patients demonstrated T1-shortening contralateral to their hemichorea-hemiballism. T2*-based sequences demonstrated unilateral hypointense signal within the striatum in four patients. One patient had mild bilateral striatal hyperintensities, while another did not show significant signal changes.
Conclusion:
It is important for the radiologist to be aware of the signal changes that can be seen on T2*-based sequences in hyperglycemia-induced hemochorea-hemiballism.

