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Acute aluminum encephalopathy in an uremic patient
J M Campistol1, A Cases, A Botey
1Nephrology Service, Hospital Clinic, Barcelona, Spain.
Nephron
|January 1, 1989
Abstract:
A patient on maintenance hemodialysis developed an acute encephalopathy closely related to a rapid increase in serum aluminum levels. Aluminum hydroxide and sucralfate had been given in large amounts for the treatment of a gastrointestinal bleeding episode. The breach of the gastrointestinal barrier to aluminum absorption, the increase in gastric pH caused by cimetidine, and the presence of gastric telangiectasia acting together in a uremic patient could have precipitated the acute aluminum encephalopathy.