Related Experiment Video
Updated: Mar 12, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Canceled coronary computed tomography angiography: Downstream testing and outcomes
Manuja Premaratne1, Montana Mason2, Alomgir Hossain2
1Department of Medicine (Cardiology), University of Ottawa Heart Institute, Ottawa, Canada; Department of Medicine (Cardiology), Frankston Hospital, Frankston, Australia.
Patients with canceled coronary computed tomography angiography (CCTA) due to severe calcification face high risks of death and heart attack. Further cardiac diagnostic testing (CAD) may improve patient outcomes.
Area of Science:
- Cardiology
- Medical Imaging
- Public Health
Background:
- Downstream resource utilization and patient outcomes following canceled coronary computed tomography angiography (CCTA) are understudied.
- Severe coronary calcification is a common reason for CCTA cancellation.
Purpose of the Study:
- To investigate downstream resource utilization and patient outcomes after CCTA cancellation due to severe coronary calcification.
Main Methods:
- Prospective enrollment in a cardiac CT registry.
- Follow-up of patients whose CCTA was canceled due to severe coronary calcification.
- Assessment of downstream resource utilization and a composite of all-cause mortality and non-fatal myocardial infarction (MI).
Main Results:
- 453 patients were followed for a median of 36 months; 62 events (41 deaths, 21 MIs) occurred (annualized rate 4%).
- 320 patients underwent downstream cardiac diagnostic testing (CAD).
- Downstream CAD testing was associated with fewer events (9.7% vs. 22.4%) and was an independent predictor of event-free survival (HR: 2.58).
Conclusions:
- Patients with canceled CCTA due to severe coronary artery calcification (CAC) have elevated risks of death and MI.
- Additional cardiac diagnostic testing (CAD) appears linked to improved outcomes in this high-risk group.
More Related Videos
04:40Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
09:32Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
Published on: December 9, 2021
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease V: Interprofessional Care
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Cardiac Catheterization I: Pre-Procedure Overview
Acute Coronary Syndrome IV: Interprofessional Care