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Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
Published on: February 26, 2018
Imaging in extrapulmonary tuberculosis.
Sanjay Gambhir1, Mudalsha Ravina1, Kasturi Rangan1
1Sanjay Gandhi Post Graduate Institute of Nuclear Medicine, Rae Bareli Road, Lucknow, India.
Tuberculosis (TB) is a global health crisis. This review discusses imaging for diagnosing extrapulmonary TB (EPTB), aiding patient management and understanding disease progression.
Area of Science:
- Medical imaging
- Infectious diseases
- Public health
Background:
- Tuberculosis (TB) causes 1.5 million deaths globally each year.
- Extrapulmonary TB (EPTB) accounts for 20% of cases, presenting diagnostic and management difficulties.
- Mycobacterium tuberculosis exhibits complex host interactions, leading to varied disease states from latent to active.
Purpose of the Study:
- To review typical and atypical imaging features of EPTB.
- To discuss the utility of various imaging modalities in diagnosing and managing EPTB.
- To highlight the need for advanced diagnostic tools for TB.
Main Methods:
- Literature review of imaging features in EPTB.
- Discussion of established and emerging imaging techniques.
- Analysis of diagnostic and management roles of imaging modalities.
Main Results:
- Imaging plays a crucial role in identifying EPTB manifestations.
- Different modalities offer unique insights into EPTB diagnosis and monitoring.
- Understanding imaging characteristics aids in patient management.
Conclusions:
- Advanced imaging is essential for effective EPTB diagnosis and treatment monitoring.
- Further research into imaging's role in TB pathogenesis is warranted.
- Improved diagnostic tools are critical for combating the global TB burden.
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