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Updated: Mar 12, 2026

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
Published on: March 25, 2020
Association between poor wound healing and the formation of Salzmann nodules
Jini Qiu1, Rongrong Cai1, Chaoran Zhang1
1From the Department of Ophthalmology (Qiu, Zhang) and the Department of Pathology (Cai), Eye and ENT Hospital of Fudan University, and the Key Laboratory of Myopia of State Health Ministry (Qiu, Zhang), Shanghai, China.
Abstract:
We report the case of a 65-year-old woman who presented with a gray-white nodular lesion located at the site of a clear corneal incision in her left eye. Anterior segment optical coherence tomography showed prominent endothelial gaping even 5 years after cataract surgery. Based on the features of clinical and histological examinations, Salzmann nodular degeneration was diagnosed. The formation of the Salzmann nodule was thought to be related to poor healing of the surgical wound. To our knowledge, this is the first case of Salzmann nodular degeneration associated with cataract surgery.
Financial Disclosure:
None of the authors has a financial or proprietary interest in any material or method mentioned.
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