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Updated: Mar 12, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor

Michael C McLeod1, Jeffrey Aubé1, Kevin J Frankowski1

  • 1Department of Medicinal Chemistry, University of Kansas, Delbert M. Shankel Structural Biology Center, 2121 Simons Drive, Lawrence, KS 66047, United States.

Bioorganic & Medicinal Chemistry Letters
|November 15, 2016
PubMed

Keywords:
Biology-oriented synthesisCNSDecahydroquinolineRadioligand bindingSigma receptorStructure-affinity relationship

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