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A new compound from Stereum insigne CGMCC5.57
Meng-Qing Tian1, Qing-Lan Wu1, Xin Wang1
1a State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, and Key Laboratory for Microbial Resources of the Ministry of Education , Yunnan University , Kunming , China.
Natural Product Research
|November 15, 2016
Summary
Researchers investigated the fungus Stereum insigne CGMCC5.57, isolating one novel dihydrobenzofuran and six known compounds. This study details the chemical constituents of S. insigne for the first time.
Area of Science:
- Natural Product Chemistry
- Mycology
- Organic Chemistry
Background:
- Stereum insigne is a fungal species with potential for novel chemical compound discovery.
- Previous research has not extensively documented the chemical constituents of S. insigne.
Purpose of the Study:
- To isolate and characterize chemical compounds from Stereum insigne CGMCC5.57.
- To report the chemical constituents of S. insigne for the first time.
Main Methods:
- Extraction of fungal material using ethyl acetate (EtOAc) and methanol.
- Isolation of compounds using chromatographic techniques.
- Structure elucidation via High-Resolution Electrospray Ionization Mass Spectrometry (HRESIMS) and 1D/2D Nuclear Magnetic Resonance (NMR) spectroscopy.
Main Results:
- One new dihydrobenzofuran derivative (compound 1) was isolated.
- Six known compounds (compounds 2-7) were identified.
- The structures were confirmed through comprehensive spectroscopic analysis.
Conclusions:
- This study provides the first detailed report on the chemical constituents of the fungus Stereum insigne.
- The identified compounds, including a novel dihydrobenzofuran, contribute to the known chemical diversity of fungal metabolites.
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