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A comparison between capsule endoscopy and double balloon enteroscopy using propensity score-matching analysis in

Yuki Kakiya1, Masatsugu Shiba1, Junichi Okamoto2

  • 1a Department of Gastroenterology , Osaka City University Graduate School of Medicine , Osaka , Japan.

Scandinavian Journal of Gastroenterology
|November 15, 2016
PubMed

Insights

Double balloon enteroscopy (DBE) shows higher diagnostic yield than capsule endoscopy (CE) for obscure gastrointestinal bleeding (OGIB). DBE may be a more effective and safer diagnostic tool for patients with previous OGIB.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Diagnostic Yield

Background:

  • Obscure gastrointestinal bleeding (OGIB) diagnosis has improved with capsule endoscopy (CE) and double balloon enteroscopy (DBE).
  • The comparative efficacy of CE versus DBE for patients with prior OGIB is not well-established.

Purpose of the Study:

  • To compare the diagnostic yield of DBE and CE in patients with a history of OGIB.
  • To determine the superior endoscopic modality for diagnosing recurrent obscure gastrointestinal bleeding.

Main Methods:

  • Retrospective evaluation of 223 patients with previous OGIB treated between May 2007 and March 2012.
  • Propensity score-matching analysis to compare the diagnostic yields of CE and DBE.
  • Logistic regression analysis to assess the superiority of one modality over the other.

Main Results:

  • DBE achieved a diagnostic yield of 41.9%, significantly higher than CE's 11.6% (p < .01).
  • DBE was significantly superior to CE after propensity score matching (OR, 4.25; 95% CI, 1.43-12.6; p < .01) and adjustment (OR, 5.65; 95% CI, 1.56-20.5; p < .01).

Conclusions:

  • Double balloon enteroscopy (DBE) demonstrates greater utility than capsule endoscopy (CE) for diagnosing obscure gastrointestinal bleeding.
  • DBE may offer a safer and more effective approach for achieving a positive diagnosis in patients with a history of OGIB.
Abstract

Keywords:
Capsule endoscopydouble-balloon enteroscopyprevious obscure gastrointestinal bleedingpropensity score-matching analysis

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