Related Experiment Video
Updated: Mar 12, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
Published on: October 11, 2024
Lung transplantation for cystic fibrosis: an update
Cecilia Chaparro1, Shaf Keshavjee2
1a Lung Transplant Respirologist - Cystic Fibrosis Respirologist, Toronto Lung Transplant Program, St. Michael's Hospital Adult Cystic Fibrosis Clinic - Associate Professor, Department of Medicine , University of Toronto , Toronto , Canada.
Abstract:
Today cystic fibrosis (CF) patients are surviving longer but ultimately the lung disease will progress despite new treatments. Lung transplantation, a life saving procedure, initially was not offered to CF patients due to their infectious complications and complications related to their multisystem disease. After the first CF patients were transplanted it appeared clear that CF patients had excellent outcomes. Infectious complications with multi-resistant bacteria are still a challenge for some patients which shortens survival in some cases. Better understanding and management of their unique extra pulmonary complications including other organ transplants have opened new horizons in the life of CF patients. Increasing number of CF patients are surviving longer pre and post transplant. Without doubt we will continue to learn as they present with new challenges and conditions unique to their disease. We reviewed the evolution and current status of the main aspects of lung transplant for CF patients.
Related Concept Videos
Cystic Fibrosis: Management
Sinus disease and chronic...
Kidney Transplant I: Introduction
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
Kidney Transplant II: Surgical Procedure

