Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

591
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
591
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

3.9K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.9K
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

1.1K
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
1.1K
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

450
Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
450
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

874
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
874
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

1.3K
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of Automated Software for Guttae Quantification in Fuchs Endothelial Corneal Dystrophy.

Translational vision science & technology·2026
Same author

Association between ABCDE bundle compliance and long-term outcomes: a secondary longitudinal analysis.

Intensive care medicine·2026
Same author

COUNTERPOINT: Should Pulmonary and Critical Care Medicine Fellowship Training Programs Require Advanced Cardiac Point-of-Care Ultrasound Competency? No.

Chest·2026
Same author

Rebuttal From Drs Walter, Satterwhite, and Schmidt.

Chest·2026
Same author

Corneal transplantation wound dehiscence after penetrating keratoplasty and deep anterior lamellar keratoplasty.

International ophthalmology·2025
Same author

Iron-Sulfur Clusters and Iron Responsive Element Binding Proteins Mediate Iron Accumulation in Corneal Endothelial Cells in Fuchs Dystrophy.

Investigative ophthalmology & visual science·2025

Related Experiment Video

Updated: Mar 12, 2026

Non-Invasive Endotracheal Administration of Lipopolysaccharide to Induce Acute Lung Injury in Rodents
04:10

Non-Invasive Endotracheal Administration of Lipopolysaccharide to Induce Acute Lung Injury in Rodents

Published on: December 5, 2025

257

Managing Acute Lung Injury.

Gregory A Schmidt1

  • 1Critical Care, Division of Pulmonary Diseases, Critical Care, and Occupational Medicine, Department of Internal Medicine, Carver College of Medicine, University of Iowa Hospitals and Clinics, University of Iowa, C33-GH, 200 Hawkins Drive, Iowa City, IA 52242, USA.

Clinics in Chest Medicine
|November 16, 2016
PubMed
Summary
This summary is machine-generated.

Mechanical ventilation for acute respiratory distress syndrome (ARDS) limits lung injury by using small tidal volumes. Higher positive end-expiratory pressure (PEEP) can improve lung recruitment and gas exchange in ARDS patients.

Keywords:
Acute lung injuryAcute respiratory distress syndromeLung-protective ventilationMechanical ventilationProne ventilationRespiratory failure

More Related Videos

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

763
Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury
09:16

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury

Published on: February 26, 2017

10.2K

Related Experiment Videos

Last Updated: Mar 12, 2026

Non-Invasive Endotracheal Administration of Lipopolysaccharide to Induce Acute Lung Injury in Rodents
04:10

Non-Invasive Endotracheal Administration of Lipopolysaccharide to Induce Acute Lung Injury in Rodents

Published on: December 5, 2025

257
Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

763
Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury
09:16

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury

Published on: February 26, 2017

10.2K

Area of Science:

  • Critical Care Medicine
  • Pulmonary Medicine
  • Mechanical Ventilation

Background:

  • Acute respiratory distress syndrome (ARDS) management requires lung-protective strategies.
  • Limiting lung overdistention is a cornerstone of mechanical ventilation in ARDS.
  • Assessing lung recruitment potential is crucial for optimizing ventilation.

Purpose of the Study:

  • To outline a foundational approach to mechanical ventilation in ARDS.
  • To describe strategies for optimizing positive end-expiratory pressure (PEEP) for lung recruitment.
  • To detail rescue therapies when conventional ventilation is insufficient.

Main Methods:

  • Limiting tidal volumes or transpulmonary pressures to prevent overdistention.
  • Assessing the potential for lung recruitment with increasing PEEP.
  • Utilizing the stress index to guide PEEP adjustments for recruitment-derecruitment.
  • Employing high PEEP tables as an alternative strategy.
  • Considering rescue therapies like extracorporeal membrane oxygenation (ECMO), inhaled vasodilators, or high-frequency oscillatory ventilation (HFOV).

Main Results:

  • Mechanical ventilation strategies aim to prevent lung overdistention.
  • PEEP titration based on lung recruitment potential can improve gas exchange.
  • Stress index monitoring can guide PEEP adjustments.
  • Rescue therapies are reserved for refractory ARDS cases.

Conclusions:

  • An integrated approach to ARDS ventilation considers disease severity and patient response.
  • Optimizing PEEP is key to enhancing lung recruitment and gas exchange.
  • Rescue therapies provide options for severe ARDS cases unresponsive to initial management.