Related Experiment Video

Updated: Mar 12, 2026

Intratracheal Instillation of Stem Cells in Term Neonatal Rats
04:27

Intratracheal Instillation of Stem Cells in Term Neonatal Rats

Published on: May 4, 2020

6.2K

Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia

Liya Ma1, Ping Zhou1, Josef Neu2

  • 1Department of Neonatology, Shenzhen Baoan Maternal and Child Health Hospital, China.

Paediatric Respiratory Reviews
|November 16, 2016
PubMed

Insights

Certain nutrients like vitamin A and long-chain polyunsaturated fatty acids (LCPUFAs) show promise in preventing bronchopulmonary dysplasia (BPD) in preterm infants. Further research is needed to explore other nutrients for BPD prevention and treatment.

Area of Science:

  • Neonatal Medicine
  • Nutritional Science
  • Pulmonology

Background:

  • Bronchopulmonary dysplasia (BPD) is a common complication in extremely preterm infants.
  • Current incidence of BPD remains high despite medical advancements, with a lack of specific treatments.
  • Nutrition is critical for lung development, and malnutrition can exacerbate BPD pathogenesis.

Purpose of the Study:

  • To review recent research on nutrients that may prevent or treat BPD.
  • To identify specific nutrients with potential therapeutic benefits for BPD.

Main Methods:

  • Literature review of studies investigating the role of various nutrients in BPD.
  • Analysis of evidence for nutrients including glutamine, cysteine, L-arginine, L-citrulline, LCPUFAs, inositol, selenium, and vitamins.

Main Results:

  • Vitamin A and LCPUFAs demonstrate potential in preventing BPD.
  • L-citrulline may offer a treatment for BPD-associated chronic pulmonary hypertension.
  • Evidence for other nutrients in BPD prevention requires further investigation.

Conclusions:

  • Specific nutrients, particularly vitamin A and LCPUFAs, show promise for BPD prevention.
  • L-citrulline presents a potential therapeutic avenue for BPD complications.
  • Additional research is necessary to fully elucidate the role of various nutrients in managing BPD.

Keywords:
Bronchopulmonary dysplasiaL-citrullinelong chain polyunsaturated fatty acidsnutrientvitamin A

More Related Videos

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

763
A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease04:21

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

Published on: August 4, 2021

7.3K

Related Concept Videos

Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.9K
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
65.7K
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
591
Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment
5.4K
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
1.4K
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
1.0K